Published on December 18, 2013

Temporary open access to research articles

open access thumb medium100 100In an effort to make research known to a broader public, Elsevier Publishers recently made some research articles open acces until January 31st, 2014. This is your chance if you are interested in some of the research performed at our lab. Currently, Jana Asselman's article "Transcription patterns of genes encoding four metallothionein homologs in Daphnia pulex exposed to copper and cadmium are time- and homolog-dependent", published in Aqutic Toxicology is open access.

Published on December 18, 2013

An approach to assess the regulatory relevance of micro-evolutionary effects in ecological risk assessment of chemicals: A case-study with Cd

etc thumb medium121 159Through ecological risk assessment (ERA) policy makers try to set protective norms for harmful chemicals in the environment. Typically, such ERAs are based on ecotoxicological research performed in the lab. However, these laboratory conditions tend to lack some measure of realism compared to the actual situation in the environment. For instance, usually only one particular individual of a species is considered in ecotoxicological tests, while in the environment multiple, different individuals are present. As with us, humans, some of these individuals can cope better with a certain chemical in the environment than others. Under continuous presence of such a chemical these, more tolerant, individuals will survive and reproduce, while the other individuals will perish. Overall, the group of individuals will become more tolerant to the chemical, a process which is called micro-evolution. In this most recent paper an approach is suggested to take this micro-evolutionary processes into account in ERA to, ultimately, make our risk assessment of chemicals in the environment more realistic.

Published on November 16, 2013

GhEnToxLab at SETAC Nashville

setaclogo2 thumb100 The Ghent University Laboratory for Environmental Toxicology will be presenting some of its research at the SETAC North America 34th Annual Meeting in Nashville, TN from 17-21 November 2013. Come and see us at the following dates and places:


Published on November 12, 2013

The initial tolerance to sub-lethal Cd exposure is the same among ten naïve pond populations of Daphnia magna, but their micro-evolutionary potential to develop resistance is very different

aquatic toxicologyDifferences between the ecological reality in the field and the controlled test conditions in the lab make ecotoxicological results sometimes difficult to extrapolate from the lab to the situation in the field. One of the conditions that are different in the field compared to the lab is the presence of different individuals of an organism. First, each of these individuals differ in their tolerance to toxic stress. Second, the presence of different individuals allow for evolution which results in a group of individuals having a higher tolerance to toxic stress compared to an unevolved group. To characterize these two problems and to investigate possible solutions to them, we compared in our latest paper the tolerance and the potential to evolve in ten groups of individuals orginating from ten natural 'field' populations in Belgium. Although the tolerance of the individuals in these ten groups is quite similar, their potential to evolve an enhanced tolerance is very different.

Published on November 6, 2013

Toxicity – biodiversity relationships unravelled

ecol lettersThe production and use of chemicals is regulated by environmental legislation so as to protect the diversity of our surface waters. Until recently, however, it was impossible to predict the relationship between chemical toxicity and the diversity of aquatic communities, which hampered effective environmental conservation. Together with an international consortium, the laboratory of environmental toxicology (, UGent) developed the first theory to predict biodiversity along gradients of toxic stress. Combining this theory to data from polluted algal communities, the scientists reveal that the variability of toxicity tolerance in these communities is five to ten times higher between individuals from the same species than between individuals from different species. The results of this research also demonstrate that this 'within-species variability' is a buffer against species loss in ecosystems polluted with chemicals. These findings, which have been published in the nr 1-ranked ecology journal 'Ecology Letters', raise important concerns regarding the use of species-based tolerance data for environmental protection and explain ecosystem resistance during chemical spills.

Published on October 18, 2013

Migration and opportunistic feeding increase PCB accumulation in arctic seabirds

ESTPolychlorinated biphenyls (POPs) are resistant towards common degradation pathways and accumulate, because of their lipophilicity, in organisms' fatty tissues. In addition, the transfer of POPs in a foodweb typically results in elevated POP concentrations at the highest trophic levels (i.e. biomagnification). Previous modeling efforts hence focused on the importance of an organism's trophic level and the lipophilicity of the chemical as predictors for the organism's POP body concentration. However, field studies have not only demonstrated that Arctic seabirds, as top predators, have elevated POP body concentrations compared to their environment, but also that POP body concentrations can differ substantially between species that occupy similar trophic levels.

Published on October 9, 2013

An investigation of the inter-clonal variation of the interactive effects of cadmium and Microcystis aeruginosa on the reproductive performance of Daphnia magna

aquatic toxicologyStressors seldomly occur isolated in the environment. In a mixture, stressors can interact with each other. That might have profound adverse effects on the animals that live in the environment. Indeed, in mixture toxicity, one plus one does not always equals two. Imagine for instance the effect of throwing a mentos candy in coke (Youtube: MythBusters - Diet Coke and mentos). The effect of both combined is much larger than what you would expect. Such (synergistic) interactions between the metal cadmium and the cyanobacterium Microcystis are what De Coninck et al. (2013) studied in their most recent paper. Cyanobacteria are toxic blue-green algae that tend to increase in occurence due to climate change (for instance, Global Water Forum).

Published on October 9, 2013

Transcription patterns of genes encoding four metallothionein homologs in Daphnia pulex exposed to copper and cadmium are time- and homolog-dependent

aquatic toxicologyIn a recent publication, Asselman et al. (2013) studied the role of metallothioneins, or metal binding proteins, in metal detoxification upon exposure to copper and cadmium. In their study, Asselman et al. (2013) used the freshwater crustacean Daphnia as a model organism but their results will help to elucidate the function of this important protein in other (higher) organisms as well. Indeed, metal pollution has significant impacts on fish (Scientific American).

Published on September 30, 2013

Development and validation of a quantitative structure–activity relationship for chronic narcosis to fish

etcQuantitative structure–activity relationship models (QSAR models) typically relate a set of predictor variables to the response variable. These models are useful tools in predictive ecotoxicology as the can be used to predict the (adverse) biological activity of a chemical (the response variable) based on the physico-chemical properties of the chemical (the predictor variables). As animal testing, and especially vertebrate testing, are generally strongly discouraged, the use of QSAR models offers an alternative. However, in ecotoxicology, QSAR models that describe the relationship between the physico-chemical properties of chemicals and their chronic toxicity to vertebrates are scarce. This lagoon in our knowledge is filled by the research described in our latest paper.

Published on September 26, 2013

Microplastic pollution in deep-sea sediments

env pollutWe have all heard the phrase: "We know more about the surface of the moon than the deep sea". Unfortunately, this is not exaggeration: the deep sea is the largest ecosystem on Earth, but also one of the least studied despite it harbouring a high biodiversity and a wealth of resources. Sadly, the deep seafloor is still, for most people, out of sight and therefore out of mind. This has encouraged the dumping of waste of all sorts into deep waters. For centuries, this was organic, degradable matter. Now, our solid wastes often contain synthetic elements, plastics in particular. In recent years, more and more reports have been published that demonstrate the large presence of plastic litter in the deep sea: the seafloor of the Mediterranean, Atlantic canyons and even Arctic waters are covered with plastic litter. Recently, our lab added another pollutant to the list: for the first time ever, microplastics were recorded in deep-sea sediments originating from several location worldwide. These results show that microplastics have penetrated the marine environment to a larger extent than previously assumed.