News

Published on October 18, 2013

Migration and opportunistic feeding increase PCB accumulation in arctic seabirds

ESTPolychlorinated biphenyls (POPs) are resistant towards common degradation pathways and accumulate, because of their lipophilicity, in organisms' fatty tissues. In addition, the transfer of POPs in a foodweb typically results in elevated POP concentrations at the highest trophic levels (i.e. biomagnification). Previous modeling efforts hence focused on the importance of an organism's trophic level and the lipophilicity of the chemical as predictors for the organism's POP body concentration. However, field studies have not only demonstrated that Arctic seabirds, as top predators, have elevated POP body concentrations compared to their environment, but also that POP body concentrations can differ substantially between species that occupy similar trophic levels.

Published on October 9, 2013

An investigation of the inter-clonal variation of the interactive effects of cadmium and Microcystis aeruginosa on the reproductive performance of Daphnia magna

aquatic toxicologyStressors seldomly occur isolated in the environment. In a mixture, stressors can interact with each other. That might have profound adverse effects on the animals that live in the environment. Indeed, in mixture toxicity, one plus one does not always equals two. Imagine for instance the effect of throwing a mentos candy in coke (Youtube: MythBusters - Diet Coke and mentos). The effect of both combined is much larger than what you would expect. Such (synergistic) interactions between the metal cadmium and the cyanobacterium Microcystis are what De Coninck et al. (2013) studied in their most recent paper. Cyanobacteria are toxic blue-green algae that tend to increase in occurence due to climate change (for instance, Global Water Forum).

Published on October 9, 2013

Transcription patterns of genes encoding four metallothionein homologs in Daphnia pulex exposed to copper and cadmium are time- and homolog-dependent

aquatic toxicologyIn a recent publication, Asselman et al. (2013) studied the role of metallothioneins, or metal binding proteins, in metal detoxification upon exposure to copper and cadmium. In their study, Asselman et al. (2013) used the freshwater crustacean Daphnia as a model organism but their results will help to elucidate the function of this important protein in other (higher) organisms as well. Indeed, metal pollution has significant impacts on fish (Scientific American).

Published on September 30, 2013

Development and validation of a quantitative structure–activity relationship for chronic narcosis to fish

etcQuantitative structure–activity relationship models (QSAR models) typically relate a set of predictor variables to the response variable. These models are useful tools in predictive ecotoxicology as the can be used to predict the (adverse) biological activity of a chemical (the response variable) based on the physico-chemical properties of the chemical (the predictor variables). As animal testing, and especially vertebrate testing, are generally strongly discouraged, the use of QSAR models offers an alternative. However, in ecotoxicology, QSAR models that describe the relationship between the physico-chemical properties of chemicals and their chronic toxicity to vertebrates are scarce. This lagoon in our knowledge is filled by the research described in our latest paper.

Published on September 26, 2013

Microplastic pollution in deep-sea sediments

env pollutWe have all heard the phrase: "We know more about the surface of the moon than the deep sea". Unfortunately, this is not exaggeration: the deep sea is the largest ecosystem on Earth, but also one of the least studied despite it harbouring a high biodiversity and a wealth of resources. Sadly, the deep seafloor is still, for most people, out of sight and therefore out of mind. This has encouraged the dumping of waste of all sorts into deep waters. For centuries, this was organic, degradable matter. Now, our solid wastes often contain synthetic elements, plastics in particular. In recent years, more and more reports have been published that demonstrate the large presence of plastic litter in the deep sea: the seafloor of the Mediterranean, Atlantic canyons and even Arctic waters are covered with plastic litter. Recently, our lab added another pollutant to the list: for the first time ever, microplastics were recorded in deep-sea sediments originating from several location worldwide. These results show that microplastics have penetrated the marine environment to a larger extent than previously assumed.

Published on September 16, 2013

Too much pharmaceuticals in the river Maas

According to the latest report of the RIWA, a Belgian-Dutch organisation of water companies, too much pharmaceuticals were measured at 10% of the sampling points. Since Since we tap a lot of drinking water from the river, this finding is disturbing, say water companies. Although our drinking water is still perfectly safe, this elevated concentration of pharmaceuticals may have an adverse effect on organisms in the environment, such as femalized male fish. In another research project, performed in 2010 and involving our laboratory, which focussed on pharmaceuticals in the water at the ports of the North Sea, traces of seven pharmaceuticals were dicovered for the first time.

Read the full article as displayed in De Standaard of August 27th, 2013 (Dutch).

Published on September 6, 2013

Epigenetics in an ecotoxiological context

mutation researchChildren of obese fathers are more likely to have chronic diseases in their later life. That was the conclusion of a remarkable study by Dr. Adelheid Soubry in BMC Medicine (De Standaard, 08/02/2013). She identified one of the mechanisms responsible to be DNA-methylation. DNA-methylation, among other mechanisms, are so-called epigenetic mechanisms. They can alter the DNA without actually altering the DNA code itself. These epigenetic mechanisms are also shown to be important in an ecotoxicological context. This was recently summarized by our post-doc Michiel Vandegehuchte in a review in Mutation Research/Genetic Toxicology and Environmental Mutagenesis.

Published on August 30, 2013

LET - Springboard to a great career

careerLMAE's PhD-student Dieter De Coninck, who will soon finish his PhD, was selected with 29 other PhD students out of over 150 applicants to attend the BASF Days Agro. This event introduces young "top of the crop" individuals into the company of BASF as a potential employer. Indeed, a PhD can be a great asset to a career. Previous LMAE PhD-students now all work at renowned companies and organizations. Dr. Michiel Claessens works now at Dupont as regulatory ecotoxicologist. Dr. ir. Roel Evens works at the Society of Environmental Toxicology and Chemistry (SETAC) and Dr. Marlies Messiaen now works at the International Zinc Association. Current top positions of some older graduates from our laboratory include two professors (Ghent University and University of Namur), two EU officials at the European Chemicals Bureau – Helsinki and two CEOs of an environmental consultancy company (Arche), a former spin-off of our lab. Their PhD and experience at LMAE has definitely been a springboard to a great career! Dieter De Coninck will defend his PhD on September 13 (invitation)!

 

Published on August 28, 2013

Building bridges across research disciplines

Exciting times are coming for the Artemia Research Community. On September 2nd, the fully sequenced genome of Artemia will be presented on the Artemia Genome Workshop. Artemia is considered a model crustacean in aquaculture just as Daphnia is considered the model crustacean in freshwater. On the Artemia Genome day, LMAE will contribute to both the presentations as well as the scientific discussion. LMAE will share her knowledge and experience on the Daphnia genome to the broad Artemia research community. Hence, LMAE will strengthen its ongoing collaboration with the Laboratory of Aquaculture and continue to facilitate cross-fertilizations between these different research domains, e.g. the AquaStress project!

More information (Dutch): Faculty of Bioscience Engineering, Ghent University

Published on August 22, 2013

Best oral presentation award on the 9th international conference on toxic cyanobacteria

awardLast week, the 9th international conference on toxic cyanobacteria (ICTC) took place in South-Africa. Being active in the research on toxic effects and genetic mechanisms of cyanobacteria, Jana Asselman represented our lab at the conference. And she did so successfully. For her oral presentation entitled "Unraveling mode of actions and toxin profiles with high throughput microarrays: a case study in Daphnia exposed to different cyanobacterial stressors", she was awarded the first prize for best oral presentation. Congratulations, Jana!

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