Metals and Metal Mixtures

Metals enter the environment through natural and anthropogenic sources and their biogeochemical behavior brings about particular challenges for ecotoxicology and risk assessment. GhEnToxLab is most particularly interested in understanding how abiotic factors (e.g. pH, temperature) influence the aquatic toxicity of metals like copper, zinc, nickel, cadmium, and lead (commonly termed metals bioavailability research), including mixtures of these metals. Based on experimental data, GhEnToxLab develops bioavailability and mixture toxicity models that can be used in policy-context by industry and regulators. In addition, GhEnToxLab is also interested in understanding the molecular and physiological mechanisms of metal toxicity, combined and interactive effects of metals and biotic stressors (like harmful algae, nutritional stress) often in a context of project climate change scenario’s, micro-evolutionary effects of metals, and extrapolation of standard metal ecotoxicity data to the population level.

Current researchers
Charlotte Nys, Tina Van Regenmortel, Cecilia Pereira, Ilias SemmouriDimitri Van de Perre, Karel Vlaeminck

Past researchers
David DeruytterJennifer Hochmuth

PhD theses
Nys, C. (2016). Bioavailability and chronic toxicity of metal mixtures in freshwater: modelling and implementation in risk assessment. Ghent University. Faculty of Bioscience Engineering, Ghent, Belgium.

Hochmuth, J. (2016). Combined effects of chemical and natural stressors on Daphnia magna in a context of global change: extrapolating from short-term experiments on individuals to long-term effects at the population level. Ghent University. Faculty of Bioscience Engineering, Ghent, Belgium.

Recent publications
Nys, C. et al. (2016). Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY35(7), 1796–1805.

Van Regenmortel, T. et al. (2015). Comparison of the capacity of two biotic ligand models to predict chronic copper toxicity to two Daphnia magna clones and formulation of a generalized bioavailability model. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY34(7), 1597–1608.

Deruytter, D. et al. (2015). Salinity and dissolved organic carbon both affect copper toxicity in mussel larvae: copper speciation or competition cannot explain everything. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY34(6), 1330–1336.

Hochmuth, J. et al. (2014). Are interactive effects of harmful algal blooms and copper pollution a concern for water quality management? WATER RESEARCH60, 41–53.

Van de Perre, D. et al. (2016). The effects of zinc on the structure and functioning of a freshwater community: A microcosm experiment. ENVIRONMENTAL TOXICOLOGY, 35(11), 2698–2712.

Van Sprang, P. et al. (2016). The derivation of effects threshold concentrations of lead for European freshwater ecosystems. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY35(5), 1310–1320.

Aquatic systems under multiple Stress: a new paradigm integrating aquaculture and ecotoxicology research (AQUASTRESS)

Mixture toxicity of metals, phase I (MET-MIX-1)